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Comparison of NAT-lncRNA knockout effect by next-generation sequencing

ABSTRACT: Analysis of different expression after lncRNA DHRS4-AS1 knockout with two strategies in immortalized human pancreatic duct epithelial cell line HPDE6-C7. The strategies include promoter-exon1 (PE) and branch point and 3‘ splicing site (BESST). The results provide transcriptome comparison between PE and BESST knockout approach, indicating the superior effect of BESST.

ORGANISM(S): Homo sapiens

PROVIDER: GSE200816 | GEO | 2022/06/30

REPOSITORIES: GEO

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Comparison of NAT-lncRNA knockout effect by Next Generation Sequencing

Project description:Analysis of different expression of mRNAs and lncRNAs after lncRNA DHRS4-AS1 knockout with two strategies in immortalized human pancreatic duct epithelial cell line HPDE6-C7. The strategies include promoter-exon1(PE) and branch point and 3‘ splicing site(BESST). The results provide transcriptome comparison between PE and BESST knockout approach, indicating the superior effect of BESST.

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