The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc
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ABSTRACT: Transcriptional analysis of BNIP3-knockdown rat NP cells and ShRNA control cells The transcriptomic analysis of the BNIP3-deficient cells showed dysregulation of cellular functions including membrane and cytoskeletal integrity, ECM-growth factor signaling, protein quality control with an overall increase in themes related to angiogenesis and innate immune response.
ORGANISM(S): Rattus norvegicus
PROVIDER: GSE202349 | GEO | 2025/05/05
REPOSITORIES: GEO
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