Single cell RNA-seq in transplanted bone marrow cells from SYNCRIP conditional mouse model

ABSTRACT: SYNCRIP depletion results in HSCs losing their self renewal abilities. Single cell sequencing was conducted in SYNCRIP WT and KO bone marrow LK (lineage -, cKit+) cells to decipher the effect of Syncrip deletion on cellular identities along the hematopoietic hierarchy, and to gain an in-depth assessment of the transcriptomic changes in different cell types upon SYNCRIP loss.

ORGANISM(S): Mus musculus

PROVIDER: GSE202421 | GEO | 2023/03/01

REPOSITORIES: GEO