Effects of the glucagon-like 1 receptor agonist exendin-4 on activated gut intraepithelial lymphocytes

ABSTRACT: Gut intraepithelial lymphocytes (IELs) are one of the few immune cell populations in the body that expresses glucagon-like 1 receptors (GLP-1R). To test the potential effects of GLP-1 on gut IEL function, we performed bulk RNA-seq on gut IELs isolated from C57BL/6J mice treated with anti-CD3 and with or without exendin-4 for 3 hours.

ORGANISM(S): Mus musculus

PROVIDER: GSE202453 | GEO | 2022/08/29

REPOSITORIES: GEO