Combining TSS-MPRA and sensitive TSS profile dissimilarity scoring to study the sequence determinants of transcription initiation

ABSTRACT: Using a transcription start site-capturing massively parallel reporter assay (TSS-MPRA) that simultaneously measures the location and frequency of transcription initiation from synthetic sequences, we carefully characterize the degree to which plasmid-based MPRAs recapitulate endogenous initiation patterns.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202564 | GEO | 2022/07/01

REPOSITORIES: GEO