MitoKO: A library of base editors for precise ablation of all protein-coding genes in the mouse mitochondrial genome

ABSTRACT: We design and apply a highly optimized library of double-stranded DNA deaminase (DddA)-derived cytosine base editors (DdCBEs) - MitoKO - to precisely ablate every mtDNA protein coding gene in the mouse mitochondrial genome

ORGANISM(S): Mus musculus

PROVIDER: GSE202643 | GEO | 2023/05/24

REPOSITORIES: GEO