BCG-activation of lymphocytes for the generation of donor-independent innate anti-tumor NK and γδ T cells
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ABSTRACT: We performed scRNA-seq to PBMCs incubated with 2 different sub-strains of BCG during 7 days. We found that iBCG co-cultures potently stimulated the proliferation of TRDV2 gamma-delta T cells, while Oncotice did not have the ability to expand this subpopulation, and mainly stimulated NK and classical T cells.
ORGANISM(S): Homo sapiens
PROVIDER: GSE203098 | GEO | 2022/12/28
REPOSITORIES: GEO
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