Induced-pluripotent stem-derived vascular endothelial cells in Down syndrome

ABSTRACT: To investigate the physiological characteristics of endothelial cells (EC) harboring trisomy 21 (T21), we establised isogenic pairs of T21-iPSCs and corrected disomy 21 (cDi21)-iPSCs We then performed gene expression profiling analysis using data obtained from RNA-seq of 5 different iPSC-derived ECs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE203257 | GEO | 2022/05/20

REPOSITORIES: GEO