Machine Learning Identifies Signatures of Macrophage Reactivity and Tolerance

ABSTRACT: A continuum of macrophage polarization states is essential tissue homeostasis. We used machine learning approaches to identify universally relevant definition of macrophage polarization states and create a predictive framework for developing macrophage-targeted precision diagnostics and therapeutics. CCDC88A was identified as a key gene in the continuum state clusters that is essential for the tolerant polarization state.

ORGANISM(S): Mus musculus

PROVIDER: GSE203423 | GEO | 2022/05/20

REPOSITORIES: GEO