Follicular lymphoma microenvironment characteristics associated with tumor cell mutations and MHC class II expression

ABSTRACT: Follicular lymphoma (FL) is a B-cell lymphoma with a complex tumor microenvironment that is rich in non-malignant immune cells. We applied single-cell RNA-sequencing to characterize the immune microenvironment of FL. This provides a classification framework of the FL microenvironment, their association with FL genotypes and antigen presentation, and informs different potential immunotherapeutic strategies.

ORGANISM(S): Homo sapiens

PROVIDER: GSE203610 | GEO | 2022/05/28

REPOSITORIES: GEO