Transcriptomics

Dataset Information

27

Global transcriptional response of E. coli to the presence and absence of bile salts


ABSTRACT: Unlike many other types of diarrheagenic bacteria that act primarily in the small intestine, O157:H7 expresses virulence primarily in the large intestine. In this study, microarray analysis is employed to examine the transcriptional response of O157:H7 to bile treatment, to gain insight into how bile affects virulence and whether bile might be temporally defending the small intestine against virulence by these bacteria. Keywords: Expression profiling of two different growth conditions Overall design: Two groups of three replicates were used: E.coli O157:H7 grown in Luria broth with or without 0.8% bile salts

INSTRUMENT(S): [E_coli_2] Affymetrix E. coli Genome 2.0 Array

ORGANISM(S): Escherichia coli  

SUBMITTER: Kate McInnerney  

PROVIDER: GSE20380 | GEO | 2012-07-31

SECONDARY ACCESSION(S): PRJNA125503

REPOSITORIES: GEO

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