Gene activation guided by nascent RNA-bound transcriptional factors

ABSTRACT: Purpose: To identify differential expressed genes after Narta activation Methods: cell lines with gene of interest inserted with TriTag were activated by Narta and then collected for RNA sequencing at 48 hpf (hours post Narta activation) Results: We found 1 and 2 (overlapped) up-regulated genes in HSPB8 and LMNA respectivelly at 48 hpf (FDR < 0.05, log2 fold change > 2) Conclusions: Narta is an activation system with high specificity

ORGANISM(S): Homo sapiens

PROVIDER: GSE204666 | GEO | 2022/05/27

REPOSITORIES: GEO