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Transcriptomics profiling of white adipose tissue of macrophage-specific Gja1 Knockout mice fed a normal chow diet (NCD) and high fat diet (HFD)

ABSTRACT: Adipose mRNA profiles of wild-type and Gja1 knockout (tamoxifen-induced Csf1r-CreER/ Gja1(floxed/floxed)) mice were generated by deep sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE204794 | GEO | 2022/06/01

REPOSITORIES: GEO

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Transcriptomics profiling of white adipose tissue of wildtype (WT) mice fed a normal chow diet (NCD) or high-fat diet (HFD)

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Project description:Gene expression in livers of male wild-type (WT) and OGG1-deficient (Ogg1-/-) mice fed either a chow diet or a high-fat diet (HFD) were examined. Mice were fed the diet for 10 weeks prior to tissue collection and were 22 weeks of age at the time of tissue collection. 24 Total samples were analyzed. We generated the following pairwise comparisons using GeneSifter: WT Chow vs Ogg1-/- Chow; WT HFD vs. Ogg1-/- HFD using t-test followed by Benjamini and Hochberg correction. An adjusted p-value less than 0.05 was considered to be statistically significant.

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Transcriptomics profiling of white adipose tissue of wildtype (WT) mice fed a normal chow diet (NCD) or high-fat diet (HFD)

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