Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The effect of Asari Radix et Rhizoma on hematopoietic stem cells in C57BL/6 mouse.

ABSTRACT: To investigate the toxicity of long-term treatment with Asari Radix et Rhizoma on hematopoietic cells, we have performed the 28 days gavage administration of AR in C57BL/6 mouse. Then, we have harvested the RBC lysed bone marrow cells, and analyzed the RNA-seq. analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE204972 | GEO | 2022/05/30

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

The effect of Asari Radix et Rhizoma on hematopoietic stem cells in C57BL/6 mouse.

Project description:The effect of Asari Radix et Rhizoma on hematopoietic stem cells in C57BL/6 mouse.

| PRJNA842910 | ENA

In-depth analysis of molecular network based on LC-MS/MS in complex systems

Project description:Ginseng Radix et Rhizoma (GR), Bufonis Venenum (BV), Epimedii Folium (EF), Aconiti Lateralis Radix Praeparata (AL) and Salviae Miltiorrhizae Radix et Rhizoma (SM)

2023-11-27 | MSV000093516 | MassIVE

Radix swinhoei

Project description:Radix swinhoei overview

| PRJNA709834 | ENA

Radix

Project description:Species divergence in the genus Radix

| PRJNA265216 | ENA

The analysis of gene transcription and the effect of drug resistance of Radix Paeoniae Rubra Decoction on Staphylococcus aureus

Project description:To study the effect of Radix Paeoniae Rubra decoction on tolerance of Staphylococcus aureus.The effect of Radix Paeoniae Rubra on the resistance of Staphylococcus aureus to oxacillin sodium was studied by millipore dilution method in this experiment.At the same time ,conducted on transcriptome analysis of Staphylococcus aureus related genes in Radix Paeoniae Rubra.And to detect the expression level of related genes of Staphylococcus aureus under the action of Radix Paeoniae Rubra by PCR technology.The tolerance of Staphylococcus aureus was decreased obviously when the concentration of Radix Paeoniae Rubra decoction was above 1mg/ml.The effect of Radix Paeoniae Rubra decoction on the expression of tolerance genes femB,pvL and gluM when the concentration of Radix Paeoniae Rubra decoction was above 4mg/ml.When rhe concentration of Radix Paeoniae Rubra is more than 1mg/ml,it can effectively reduce the resistance of Staphylococcus aureus to oxacillin sodium.The reason may be due to the effect of Radix Paeoniae Rubra on the resistance gene of Staphylococcus aureus.

2021-01-30 | GSE165791 | GEO

Identification of novel efficacy of Bupleuri Radix based on the transcriptome analysis

Project description:Transcriptomic landscapes of A549 cell line treated with Bupleuri Radix

2021-08-19 | GSE182007 | GEO

Radix auricularia

Project description:Radix auricularia Genome sequencing and assembly

| PRJNA350764 | ENA

Radix swinhoei

Project description:Radix swinhoei Genome sequencing and assembly

| PRJNA709360 | ENA

Comparison of Two Different Astragali Radix by 1H NMR based Metabolomic Approach

Project description:Astragali Radix (AR) is a commonly used herbal drug in Traditional Chinese Medicine, and widely used for the treatment of diabetes, cardiovascular diseases, nephropathy and neuropathy. The main source of AR is the dried root of Astragalus membranaceus var. mongholicus (Bge.) Hsiao in China, and both cultivated and wild ARs are used in the clinic. Systematic comparison of cultivated AR and wild AR should be performed to ensure the efficacy and safety in clinic. In this study, the chemical compositions of two different ARs, collected in Shanxi (wild) and Gansu (cultivated) Provinces, were compared by NMR based metabolic fingerprint coupled with multivariate analysis. Then SX-AR and GS-AR induced metabolic changes of endogenous metabolites in mice were also compared. The results showed that SX-AR and GS-AR differed significantly not only in the primary metabolites, but also the secondary metabolites. However, alterations of endogenous metabolites in serum, lung, liver and spleen were relatively small between them. This study provided a novel and valuable method for consistency and diversity evaluation of herbal drugs, and further studies should be conducted on the difference of polysaccharide as well as biological effect between the two kinds of ARs.

2017-01-16 | MTBLS189 | MetaboLights

RNA-seq of C57BL/6 mice splenocytes during Trypanosoma Evansi infection

Project description:We investigate changes in the single-cell transcriptomic profile of mouse (C57BL/6) splenocytes during Trypanosoma Evansi Merzoua-93 (ITMAS 150399C) infection. Infection was initiated by Intraperitoneal injection with parasites diluted in PBS. On day 0/14/42 post-injection, mice spleens were disassociated, RBC lysed to obtain the cells for 10x Chromium 3' Gene Expression Profiling

2021-10-26 | E-MTAB-10174 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data