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Tolerogenic dendritic cells protect against acute kidney injury


ABSTRACT: We use tolDCs from syngeneic (C57BL6) and allogeneic (BALB/c) mice to show potent renoprotective abilities in a ischemia reperfusion AKI model. Dendritic cells were derived from mice bone marrow and cultured for 7 days with GM-CSF and IL-4. Tolerogenic DCs were cultured in the same DC media but with the addition of VitD3 and IL10. LPS was added on day 6 and cells harvested for use or analysis on day 7.

ORGANISM(S): Mus musculus

PROVIDER: GSE205322 | GEO | 2023/07/01

REPOSITORIES: GEO

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