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Transcriptional changes in bone marrow cells upon SWI/SNF inhibition [scRNA-seq]

ABSTRACT: Despite significant therapeutic potential of SWI/SNF inhibition therapy, the off-tumor effects of SWI/SNF inhibition remain largely unknown. Here, we quantify the effects of the dual SWI/SNF ATPase inhibitor BRM014 on bone marrow cells in mice. We identify lineage-dependent effects on the B and monocyte lineages within the bone marrow.

ORGANISM(S): Mus musculus

PROVIDER: GSE205571 | GEO | 2023/01/10

REPOSITORIES: GEO

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Changes of DNA accessibility and RNA transcription upon SWI/SNF inhibition in peripheral blood and bone marrow cells [multiome]

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