Transcriptomics

Dataset Information

32

Effects of PMA on exon usage of HL60, THP-1, and U937 cells


ABSTRACT: Myeloid leukemia cell lines HL60, THP-1, and U937 undergo macrophage-like differentiation after treatment with phorbol ester. To explore genes whose exon usage was altered during macrophage differentiation, we compared exome of PMA-treated (differentated) and vehicle-treated (undifferentiated) myeloid cell lines. Overall design: HL60, THP-1, and U937 cells were treated with either phorbol 12-myristate 13-acetate (PMA,30nM) or its vehicle (DMSO) for 3 days, and subjected to exome analysis using Affymetrix human exon 1.0ST arrays.

INSTRUMENT(S): [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]

ORGANISM(S): Homo sapiens  

SUBMITTER: Hiroshi Kitamura  

PROVIDER: GSE20567 | GEO |

SECONDARY ACCESSION(S): PRJNA125221

REPOSITORIES: GEO

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