Single-cell RNA-sequencing of Mettl14 conditional knock-out retinas and matched controls
Ontology highlight
ABSTRACT: Post-transcriptional m6A methylation on mRNA plays a key role in neural development. Here, we specifically depleted Mettl14 (a key component of m6A complex) in retina progenitor cells by crossing Mettl14 fl/fl mice with the Chx10-Egfp/Cre mouse line and investigated cell type and transcriptome changes in the developing retinas using scRNA-seq.
ORGANISM(S): Mus musculus
PROVIDER: GSE206013 | GEO | 2023/05/31
REPOSITORIES: GEO
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