Transcriptomics

Dataset Information

20

Human Nephrosclerosis Triggers a Hypoxia-Related Glomerulopathy


ABSTRACT: Expression data from microdissected glomeruli to examine the role of hypoxia in glomerulosclerosis of human Nephrosclerosis (NSC). Overall design: Human Kidney biopsies of patients with NSC (n=14) and TN (n=4) were selected for RNA extraction and hybridization on Affymetrix microarrays. Gene expression data was then analysed using Genepattern and Genomatix software suites which revealed that CXCR4/CXCL12 plays a role in human NSC and therefore indicate that hypoxia contributes to glomerular damage in NSC.

INSTRUMENT(S): [HG-U133A] Affymetrix Human Genome U133A Array

ORGANISM(S): Homo sapiens  

SUBMITTER: Preethi Sankaranarayanan   

PROVIDER: GSE20602 | GEO | 2010-03-30

SECONDARY ACCESSION(S): PRJNA124773

REPOSITORIES: GEO

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