Asparagine starvation on histone methylation and gene expression
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ABSTRACT: We are determining the impact of asparagine starvation on histone H3K4 trimethylation deposition across the genome and how they may affect the gene expression. Overall design: RS4;11 cells were cultured in complete medium, asparagine-free medium or asparagine-free medium supplemented with 10 uM ferric nitrate for 24 hours. Whole cell RNA was collrected for RNA-seq and nuclear extracts were subjected to H3K4me3 ChIP-seq.
INSTRUMENT(S): Illumina NovaSeq 6000 (Homo sapiens)
ORGANISM(S): Homo Sapiens
SUBMITTER:
Ji Zhang
PROVIDER: GSE206112 | GEO | 2022-06-16
REPOSITORIES: GEO
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