Paired scRNA-seq and scTCR-seq of GP33-specific CD8 T cells in chronic LCMV infection

ABSTRACT: Chronic viral infection results in CD8 T cell exhaustion. Here, we use paired single-cell RNA sequencing (scRNA-seq) and single-cell T cell receptor sequencing (scTCR-seq) to investigate CD8 T cell phenotypic and clonal heterogeneity in multiple mice during the late stage of LCMV Clone 13 infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE206230 | GEO | 2022/10/23

REPOSITORIES: GEO