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Methyl-SNP-seq reveals dual readouts of methylome and variome at molecule resolution

ABSTRACT: We developed Methyl-SNP-seq, a technology that takes advantage of the redundancy of the double helix, to extract the methylation and sequence information from a single original DNA molecule We demonstrate the usefulness of this technology on a broad spectrum of applications ranging from allele specific methylation analysis in humans to methylation identification in complex bacterial communities.

ORGANISM(S): Clostridium acetobutylicum Escherichia coli Homo sapiens

PROVIDER: GSE206253 | GEO | 2022/06/19

REPOSITORIES: GEO

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