Chromatin profiling following SWI/SNF inhibition in neuroblastoma cells [ChIP-seq]

ABSTRACT: To assess the genome-wide effects of SWI/SNF activity in MYCN-amplified neuroblastoma cells, we performed ChIP-seq in IMR-32 cells treated with either DMSO or the SWI/SNF inhibitor BRM014. Pronounced loss of chromatin occupancy was observed for members of the neuroblastoma core regulatory circuitry within 1 hour.

ORGANISM(S): Homo sapiens

PROVIDER: GSE206310 | GEO | 2023/10/24

REPOSITORIES: GEO