Nano-silica particles synergistically IgE-mediated mast cell activation

ABSTRACT: To deeply investigate the details of the nano-SiO2 effects, we examined the gene expression profile alterations after nano-SiO2 treatment in BMMCs. The difference analysis between the groups showed that 285 genes were significantly expressed after treatment with nano-SiO2. Compared with the blank group, both nano-SiO2 exposure and DNP-HSA stimulation increased the expression of genes related to the MAPK signaling pathway in mast cells to varying degrees.

ORGANISM(S): Mus musculus

PROVIDER: GSE206630 | GEO | 2022/07/05

REPOSITORIES: GEO