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RNASeq to investigate ETV4 and ETV5 function in human foetal lung tip progenitor cells

ABSTRACT: In order to understand transcription factor ETV4 and ETV5 function, we have knocked down ETV4 and ETV5 synergistically in human foetal lung tip progenitor organoids using an inducible CRISPRi system. We discovered that ETV double knockdown led to organoid cell self-renewal defects

ORGANISM(S): Homo sapiens

PROVIDER: GSE207179 | GEO | 2022/07/02

REPOSITORIES: GEO

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RNASeq to investigate ETV4 and ETV5 function in human foetal lung tip progenitor cells

Project description:RNASeq to investigate ETV4 and ETV5 function in human foetal lung tip progenitor cells

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Murine ES Cells: Control vs. ETV4/5 double KO

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Project description: Not available

| S-EPMC2875840 | biostudies-other