ECP as a treatment for immune checkpoint inhibitor-induced colitis [array]

ABSTRACT: Mice were treated with DSS and anti-PD1 to induce colitis, comparable to patients suffering from ICI-induced immune-related adverse events. ECP showed beneficial effects in patients. Mice were transplanted with ECP-tretaed cells as treatment and RNA was extracted from colitis tissue to anravel the mechanisms causing the reduction of colitis severity.

ORGANISM(S): Mus musculus

PROVIDER: GSE207823 | GEO | 2024/11/27

REPOSITORIES: GEO