Effect of global Caspase-1 (Casp1) knockout (KO) on kidney gene expression in an orthologous mouse model of polycystic kidney disease (PKD)

ABSTRACT: We examined the effects of global Caspase-1 KO on kidney gene expression in an orthologous mouse model of PKD, which carries a homozygous knockin missense mutation, Pkd1RC/RC , that matches a human disease allele, PKD1 p.R3277C ("RC").

ORGANISM(S): Mus musculus

PROVIDER: GSE207957 | GEO | 2022/09/30

REPOSITORIES: GEO