Evaluation of mouse laryngeal inflammation upon low and high dose cigarette smoke exposures via NanoString analysis

ABSTRACT: Cigarette smoking is a major risk factor for laryngeal diseases. Despite well-documented cigarette smoke (CS) induced laryngeal histopathological changes in animal models and humans, the underlying immunopathological mechanisms remain largely unexplored. The goal of this study was to evaluate inflammatory and immune cell responses in a CS-exposed larynx. Specifically, we investigated these responses in the mouse larynx after a 4-week subacute low (LD) and high-dose (HD) whole-body mainstream CS exposure.

ORGANISM(S): Mus musculus

PROVIDER: GSE208079 | GEO | 2022/07/13

REPOSITORIES: GEO