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RNA-seq analysis of transcriptomes of WT and Foxp3∆2 Treg cells in spleen and LNs

ABSTRACT: We performed RNA-seq analysis of Tregs isolated from Foxp3RFP/∆2Foxp3∆CNS1-cre-Thy1.1Rosa26LSL-YFP female mice. CD4+YFP+RFP+ (WT Tregs) and CD4+YFP+RFP- (Foxp3∆2 Tregs) cells were sorted from lymph nodes and spleen to a typical purity of >95% We detected 638 differentially expressed genes (DEGs, FDR < 0.05) between Foxp3∆2 and WT Tregs

ORGANISM(S): Mus musculus

PROVIDER: GSE208094 | GEO | 2023/07/01

REPOSITORIES: GEO

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