Protocol for Mapping Protein-DNA Interactions with Directed Methylation with Long-read Sequecing (DiMeLo-seq)

ABSTRACT: DiMeLo-seq uses a protein A Hia5 fusion to direct adenine methylation at specific regions of the genome using antibodies for chromatin-bound factors. Adenine and cytosine methylation are then read out by methylation-sensitive long-read sequencing.

ORGANISM(S): Homo sapiens Drosophila melanogaster

PROVIDER: GSE208125 | GEO | 2022/07/18

REPOSITORIES: GEO