Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNASeq of blood by Mesenchymal stem cells treatment on DNCB induced mice model

ABSTRACT: Evaluate the therapeutic effects of different delivery route of MSC treantment in DNCB induced atopic dermatitis mice model.

ORGANISM(S): Mus

PROVIDER: GSE209517 | GEO | 2023/05/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

RNASeq of skin tissues by Mesenchymal stem cells treatment on DNCB induced mice model

Project description:Evaluate the therapeutic effects of different delivery route of MSC treantment in DNCB induced atopic dermatitis mice model.

2023-05-01 | GSE209704 | GEO

Metagenome sequencing of feces of mouse treated D-galactose or not

Project description:D-galactose orally intake ameliorate DNCB-induced atopic dermatitis by modulating microbiota composition and quorum sensing. The increased abundance of bacteroidetes and decreased abundance of firmicutes was confirmed. By D-galactose treatment, Bacteroides population was increased and prevotella, ruminococcus was decreased which is related to atopic dermatitis.

2022-04-29 | E-MTAB-11632 | biostudies-arrayexpress

Genomic profiling of the overlap phenotype between psoriasis and atopic dermatitis

Project description:Clinical overlaps between psoriasis and atopic dermatitis are sometimes undiscernible, and there is no consensus whether to treat the overlap phenotype as psoriasis or atopic dermatitis. We enrolled patients diagnosed with either psoriasis or atopic dermatitis, and clinically re-stratified them into classic psoriasis, classic atopic dermatitis, and the overlap phenotype between psoriasis and atopic dermatitis. We compared gene expression profiles of lesional and nonlesional skin biopsy tissues between the three comparison groups. Global mRNA expression and T-cell subset cytokine expression in the skin of the overlap phenotype were consistent with the profiles of psoriasis and different from the profiles of atopic dermatitis. Unsupervised k-means clustering indicated that the best number of distinct clusters for the total population of the three comparison groups was two, and the two clusters of psoriasis and atopic dermatitis were differentiated by gene expression. Our study suggests that clinical overlap phenotype between psoriasis and atopic dermatitis has dominant molecular features of psoriasis, and genomic biomarkers can differentiate psoriasis and atopic dermatitis at molecular levels in patients with a spectrum of psoriasis and atopic dermatitis.

2023-06-24 | GSE182740 | GEO

RNAseq analysis of total skin from control or JunBdep mice

Project description:RNA was isolated from total skin of control or JunBdep mice at 6-7 months of age when the skin of mutant mice resemble Atopic Dermatitis.

2019-10-16 | GSE136657 | GEO

EGR1 increases the innervation density of epidermal sensory neurons via upregulation of ARTN in keratinocytes in atopic dermatitis

Project description:Atopic dermatitis (AD) is the chronic inflammatory skin disease accompanied with severe pruritus. To explore the roles of EGR1 in atopic dermatitis and the relationship between EGR1 and pruritus-scratching behavior, we used a atopic dermatitis-like mouse model driven by house dust mite (HDM) treatment in wild type and EGR1 KO mice, followed with RNA-sequencing analysis.

2024-01-15 | GSE214750 | GEO

Staphylococcus aureus

Project description:Atopic Dermatitis

| PRJNA512846 | ENA

Microarray transcriptome profiling of atopic dermatitis and psoriasis patients compared to healthy volunteers.

Project description:Characteization host-microbiome interactions in patients with allergic (model: atopic dermatitis) and autoimmune (model: psoriasis) diseases by integration of microarray transcriptome data with 16S microbial profiling. 6mm punch biopsies were collected from the skin of atopic dermatitis and psoriasis patients alongside healthy volunteers, and subjected to analysis using Affymetrix Human Gene ST 2.1 arrays.

2019-09-11 | E-MTAB-8149 | biostudies-arrayexpress

Genome-wide analysis of gene expression in the cervical spinal cord of a mouse model of atopic dermatitis

Project description:Genome-wide analysis of gene expression in the cervical spinal cord of atopic dermatitis model mice was performed. Results provide important information for understanding of molecular mechanisms of the symptoms of atopic dermatitis.

2015-07-17 | GSE70114 | GEO

Optimizing single-cell transcriptomic discrimination of atopic dermatitis versus psoriasis vulgaris

Project description:Optimizing single-cell transcriptomic discrimination of atopic dermatitis versus psoriasis vulgaris

| EGAS00001007487 | EGA

641c8b17-6b33-41c8-a60a-ec83a72e5ede - samples

Project description:Optimizing single-cell transcriptomic discrimination of atopic dermatitis versus psoriasis vulgaris

| EGAD00001011104 | EGA