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The dural innate immune barrier protects the CNS from systemic virus invasion [CD45_10X]

ABSTRACT: To investigate cellular landscape of dural immune cells, dural immune cells from 30 P28 male mice and 30 P7 male mice were FACS sorted and single-cell RNA seqs were performed

ORGANISM(S): Mus musculus

PROVIDER: GSE209571 | GEO | 2022/07/25

REPOSITORIES: GEO

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The dural innate immune barrier protects the CNS from systemic virus invasion [EC_10X]

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The dural innate immune barrier protects the CNS from systemic virus invasion [MHCII_10X]

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Distinct Functional Properties of Perinatal vs Adult Adipose Progenitors

Project description:We previously identified functional distinct sub-popultions in adult male gWAT Pdgfrb+ cells utilizing the MuralChaser lineage tracking system and Single-cell RNA-seq. To examine the cellular altas and developmental aspects of male gWAT, we performed Single-cell RNA-seqs on different developing stage of gWAT (P3,P7 and 5-week). To examine the mesothelial origin hypothesis of gWAT, we also performed Single-cell RNA-seq on P7 gWAT associated mesothelial cells.

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Differential expression of stem cell-specific genes in P7 and P28 dentate gyrus neural progenitors

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2009-03-10 | E-GEOD-15085 | biostudies-arrayexpress

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The dural innate immune barrier protects the CNS from systemic virus invasion

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-07-25 | GSE209575 | GEO

Role of human dural fibroblasts in the angiogenic responses of human endothelial cells: an in vitro dural model for EDAS

Project description:To determine whether dural fibroblasts (DuF) under IL-1β-mediated wound conditions, release pro-angiogenic factors, and promote angiogenic properties in human endothelial cells (ECs). DuF were stimulated by pro-inflammatory cytokines interleukin (IL)-1β, and transcriptome sequencing was then used to identify the differentially expressed genes in the DuF with/without IL-1β stimulation (DuFCon/DuFIL1b)

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