Targeting the unwindosome by mebendazole is a vulnerability of chemoresistant hepatoblastoma

ABSTRACT: We identified mebendazole as a drug to circumvent chemoresistance in hepatoblastoma cell lines that are resistant to cisplatin. In order to identify the mechanistic basis of mebendazole function, we performed gene expression analysis of three mebendazole-treated hepatoblastoma cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE209824 | GEO | 2022/07/28

REPOSITORIES: GEO