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Genome-wide analysis of ARNT/HIF binding sites in BeWo cells cultured under low oxygen

ABSTRACT: In this study, we provide new insight into the role of the hypoxia-inducible factor (HIF) complex in the inhibition of syncytiotrophoblast formation under low oxygen. Through a genome-wide analysis of binding sites for the aryl hydrocarbon nuclear receptor translocator (ARNT; a key component of HIF), we identified the downstream targets of ARNT/HIF that potentially mediate its repressive effect on syncytialization.

ORGANISM(S): Homo sapiens

PROVIDER: GSE209936 | GEO | 2023/03/20

REPOSITORIES: GEO

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