3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances the TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury

ABSTRACT: This study investigated the therapeutic value of a candidate CRM, 3,4-dimethoxychalcone (3,4-DC), in functional recovery after SCI and its underlying mechanism. RNA sequencing was used to identify the mechanisms of 3,4-DC in SCI.

ORGANISM(S): Mus musculus

PROVIDER: GSE210033 | GEO | 2022/08/01

REPOSITORIES: GEO