Tissue-resident memory T-cells in pancreatic ductal adenocarcinoma co-express PD-1 and TIGIT and inhibition is reversible by dual antibody blockade 

ABSTRACT: An in-depth investigation of the pancreatic ductal adenocarcinoma tumour microenvironment highlights PD-1 and TIGIT, or their corresponding ligands, as potential targets for combinatorial monoclonal antibody therapy to treat this devastating disease. 

ORGANISM(S): Homo sapiens

PROVIDER: GSE210199 | GEO | 2023/01/24

REPOSITORIES: GEO