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Somatic variants of MAP3K3 are sufficient to cause cerebral cavernous malformations

ABSTRACT: To further explore the underlying molecular pathways altered by MAP3K3I441M in endothelial cells, the mouse endothelial cell line bEnd.3 was first infected with lentivirus-MAP3K3I441M (LV- MAP3K3I441M-P2A-EGFP; LV-EGFP was used as the control). Total RNA from these cells was then subjected to RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE210673 | GEO | 2023/04/18

REPOSITORIES: GEO

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