Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The ATAC epigenomic profiling of Capitella teleta development

ABSTRACT: Capitella teleta is a model specie in marine annelids research, to gain insight into its development, we performed time-course ATAC-seq ranging from 64 cell to stage 8 larvae, to profiling the gene regulation dynamics

ORGANISM(S): Capitella teleta

PROVIDER: GSE210814 | GEO | 2022/11/16

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

The developmental transcriptome profiling of Capitella teleta

Project description:Capitella teleta is a model specie in marine annelids research, to gain insight into its development, we performed time-course RNA-seq ranging from 64 cell to stage 7 larvae, to profiling the gene expression dynamics

2022-11-16 | GSE192478 | GEO

Developmental systesms drift in dorsoventral patterning is linked to transitions to autonomous development in Annelida

Project description:The Bone Morphogenetic Protein (BMP) pathway is the ancestral signalling defining the dorsoventral axis in bilaterally symmetrical animals. However, Spiralia, a large bilaterian clade including molluscs and annelids, uses the Fibroblast Growth Factor pathway and ERK1/2 as the ancestral cue to establish their posterodorsal side. How this profound change in axial patterning evolved and what it implied for BMP’s developmental role remains elusive. Here, we studied four annelid species and combined disruption of the BMP and Activin/Nodal pathways with transcriptomics and blastomere deletions to demonstrate that BMP is ancestrally downstream of ERK1/2 and promotes dorsoventral development in Spiralia. Importantly, this signalling hierarchy is lost in annelids that secondarily transitioned into a maternally controlled, autonomous development. While some, like Capitella teleta, use Activin/Nodal, the annelid Platynereis dumerilii relies on BMP to establish dorsoventral polarity only in the head. Unexpectedly, this divergence in upstream axial regulators implied extensive rewiring of downstream targets, as inferred by comparing C. teleta and Owenia fusiformis. Our data clarify the ancestral BMP’s axial role in Spiralia, unveiling a potential causal link between parallel shifts to autonomous cell-fate specification in early development and the emergence of developmental system drift, a pervasive yet poorly understood phenomenon in animal embryogenesis.

2026-03-18 | GSE297936 | GEO

Functional evidence that Activin/Nodal signaling is required for establishing the dorsal-ventral axis in the annelid Capitella teleta

Project description:Transcript abundances were examined in single Capitella teleta embryos at three timepoints: 8-cell, 16-cell, and 32-cell stage.

2020-08-31 | GSE154251 | GEO

Capitella teleta

Project description:Capitella teleta overview

| PRJNA176168 | ENA

The ATAC epigenomic profiling of Capitella teleta development

Project description:The ATAC epigenomic profiling of Capitella teleta development

| PRJNA867678 | ENA

Capitella teleta microbiome

Project description:Capitella teleta microbiome Metagenome

| PRJNA488481 | ENA

Project description:Capitella teleta RNA sequencing of competent and pre-competent larvae

| PRJNA379706 | ENA

A dynamic histone-based chromatin regulatory toolkit underpins genome and developmental evolution in an invertebrate clade

Project description:The dynamic addition and removal of posttranslational modifications on eukaryotic histones define regulatory regions that play a central role in genome and chromatin biology. Here, we present the histone variation in the adult landscapes of histone posttranslational modifications, as revealed by quantitative mass spectrometry in O. fusiformis and Capitella teleta. MTD keywords Histone

2025-05-18 | PXD064021 | Pride

Capitella teleta

Project description:Capitella teleta Genome sequencing and assembly

| PRJNA175705 | ENA

Project description:Microbial community changes caused by Capitella teleta in marine sediment microcosms

| PRJNA575020 | ENA