Unknown

Dataset Information

34

NF1 inactivation in adult acute myelogenous leukemia


ABSTRACT: Purpose: This study was conducted to identify novel genes with importance to the biology of adult acute myelogenous leukemia (AML). Conclusions: NF1 null states are present in 7/95=7% of adult AML and delineate a disease subset that could be preferentially targeted by Ras or mTOR-directed therapeutics. Overall design: Experimental design: We analyzed DNA from highly purified AML blasts and paired buccal cells from 95 patients for recurrent genomic microdeletions using ultra-high density Affymetrix SNP 6.0 array-based genomic profiling. 006, 096 and 136 normal Samples have been excluded from study.

INSTRUMENT(S): [GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: Sami N Malek  

PROVIDER: GSE21107 | GEO | 2010-12-02

SECONDARY ACCESSION(S): PRJNA126677

REPOSITORIES: GEO

Similar Datasets

2010-12-02 | E-GEOD-21107 | ArrayExpress
2010-05-26 | E-GEOD-19730 | ArrayExpress
2010-05-26 | GSE19730 | GEO
| GSE96738 | GEO
2010-11-30 | GSE23452 | GEO
2005-02-05 | E-MEXP-258 | ArrayExpress
| GSE32029 | GEO
2015-03-01 | E-GEOD-61323 | ArrayExpress
2017-05-01 | E-GEOD-78901 | ArrayExpress
2013-02-12 | E-GEOD-41646 | ArrayExpress