Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner [1]

ABSTRACT: Loss of SAMHD1 causes chronic activaiton of the MDA5/MAVS dsRNA sensing pathway, only when cGAS/STING signaling is intact.

ORGANISM(S): Mus musculus

PROVIDER: GSE211208 | GEO | 2022/08/18

REPOSITORIES: GEO