Genomics

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Transcriptional changes in Wnt antagonism- and TGFβ agonism-induced MSC chondrogenesis.


ABSTRACT: Wnt/β-catenin signaling is important in skeletal related-tissue development. We have found that Wnt/β-catenin antagonist XAV could replace traditionally used TGFβ3 as chondrogenic inducer. Here we applied gene expression array to characterize transcriptomic changes between XAV- and TGFβ-induced chondrogenic differentiation in human bone marrow (BM) and induced pluripotent stem cell (iPSC) derived MSCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE211559 | GEO | 2023/01/04

REPOSITORIES: GEO

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