Methylation profiling

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DNA Methylation Profiling in Rare Sellar Esthesioneuroblastoma


ABSTRACT: Histologic diagnosis of sellar masses can be challenging, particularly in rare neoplasms and tumors without definitive biomarkers. DNA methylation has recently emerged as a useful diagnostic tool. To illustrate the clinical utility of machine-learning-based DNA methylation classifiers, we report a rare case of primary sellar esthesioneuroblastoma diagnosed by DNA methylation classificiation but histologically mimicking a nonfunctioning pituitary adenoma.

ORGANISM(S): Homo sapiens

PROVIDER: GSE211634 | GEO | 2022/10/04

REPOSITORIES: GEO

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