Blocking LAIR1 signaling in immune cells inhibits tumor development

ABSTRACT: LAIR1 is an inhibitory immune cell receptor. We used single cell RNA sequencing (scRNA-seq) to analyze the immune cell distribution in the implanted B16 tumor tissues of Vav-cre human LAIR1 transgenic and LAIR1-/- C57bl/6j mice after control or anti-LAIR1 blocking antibody treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE212516 | GEO | 2022/10/27

REPOSITORIES: GEO