Gene expression of Mycobacterium tuberculosis and infected macrophages using bacilli log phase and NRP1/NRP2 phases

ABSTRACT: In order to stablish differences between M. tuberculosis gene expression when different growth conditions are used in a macrophage infection model (Log, NRP1 and NRP2 stages), we have designed a whole M. tb genome microarray combined with 173 human genes. RNA from bacilli and macrophages was isolated at 24h and 48h post infection. Microarrays were hybridized usign a combination of mycobacterial and human RNA and expression level was assesed using the Agilent SureScan Microarray Scanner. Then, data were normalized and differential expression was analyzed.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE212637 | GEO | 2025/12/01

REPOSITORIES: GEO