Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of interneurons in the mouse prefrontal cortex

ABSTRACT: TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in neurons in the prefrontal cortex of adult Crh-IRES-Cre mice (Jackson 012704). This work was supported by the Howard Hughes Medical Institute (N.H) and NIDA UG3-UH3 DA048385

ORGANISM(S): Mus musculus

PROVIDER: GSE212780 | GEO | 2022/09/16

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional profiling of neurons in the thalamus of a Cbln1-TRAP (NIDA030) mouse line

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in neurons in the thalamus of adult Cbln1-EGFP/Rpl10a (NIDA030) mice. This work was supported by a grant from the National Institute on Drug Abuse P30DA035756 to N.H.

2019-08-31 | GSE136699 | GEO

Transcriptional profiling of neurons in the thalamus of a Slc17a6-TRAP (JX883) mouse line

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in neurons in the thalamus of adult Slc17a6-EGFP/Rpl10a (JX883) mice. Slc17a6 is also known as Vglut2. This work was supported by a grant from the National Institute on Drug Abuse P30DA035756 to N.H.

2019-08-31 | GSE136690 | GEO

Transcriptional profiling of neurons in the mouse cortex-amygdala transition zone (CxA)

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in neurons in the cortex-amygdala transition zone (CxA) of adult Lypd1-EGFP/Rpl10a (OI82) mice. This work was supported by a grant from the National Institute on Drug Abuse P30DA035756 to N.H.

2019-08-27 | GSE136301 | GEO

Transcriptional profiling of neurons in the rostral pons of a Cbln2-TRAP (NIDA172) mouse line

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in neurons in the rostral pons of adult Cbln2-EGFP/Rpl10a (NIDA172) mice. This brain area includes the locus coeruleus and parabrachial nuclei. This work was supported by a grant from the National Institute on Drug Abuse P30DA035756 to N.H.

2019-08-31 | GSE136700 | GEO

Transcriptional profiling of interneurons in the cerebral cortex of Htr3a-Cre (NO176) mice

Project description:TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in interneurons in the cerebral cortex of adult Htr3a-Cre (NO176) mice x Rosa26-LSL-EGFP/Rpl10a mice

2019-12-16 | GSE141874 | GEO

Transcriptional profiling of neurons in the prefrontal cortex of an Slc17a6-TRAP (JX883) mouse line

2019-12-10 | GSE141671 | GEO

Genome-wide translational profiling of amygdala Crh-expressing

Project description:Here we translationally profiled the transcriptome of Crh-expressing neurons (Crh neurons) within the CeA following fear conditioning (FC) and fear extinction (EXT) in mice using translating ribosome affinity purification (TRAP) followed by RNA sequencing. A tone alone group (TA) was used as a control group.

2020-09-05 | GSE157021 | GEO

Generation and characterization of a mouse line for monitoring translation in dopaminergic neurons.

Project description:We developed a mouse line targeting midbrain dopamine neurons for Translating Ribosome Affinity Purification (TRAP). Here, we briefly report on the basic characterization of this mouse line including confirmation of expression of the transgene in midbrain dopamine neurons and validation of its effectiveness in capturing mRNA from these cells. We also report a translational profile of these neurons which may be of use to investigators studying the gene expression of these cells. Finally, we have donated the line to Jackson Laboratories for distribution and use in future studies.

2017-08-20 | GSE99927 | GEO

Transcriptional profiling of neurons in the hypothalamus of a Lhx5-TRAP (DT154) mouse line

2019-09-10 | GSE137080 | GEO

Transcriptional profiling of neurons in the midbrain of a Stard8-TRAP (ES2342) mouse line

2019-09-10 | GSE137079 | GEO