Hippocampus-specific loss of intellectual disability-related gene Brpf1 impaired spatial and contextual learning

ABSTRACT: To help explain the dominant symptom-intellectual disability found in those patients with BRPF1 mutations, we used a genetically modified mouse model and used several methods to study the effect caused by BRPF1 knockout. We then performed gene expression profiling analysis using data obtained from RNA-seq of two genotypes of mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE212983 | GEO | 2022/09/12

REPOSITORIES: GEO