Cellular landscapes of non-diseased human cardiac valves from end-stage heart failure-explanted heart

ABSTRACT: Exploring the mechanisms of valvular heart disease (VHD) at the cellular level may be useful to identify new therapeutic targets; however, the comprehensive cellular landscape of non-diseased human cardiac valve leaflets remains unclear. The cellular landscapes of non-diseased human cardiac valve leaflets (five aortic valves, five pulmonary valves, five tricuspid valves, and three mitral valves) from end-stage heart failure patients undergoing heart transplantation were explored using single-cell RNA sequencing (scRNA-seq)

ORGANISM(S): Homo sapiens

PROVIDER: GSE213128 | GEO | 2022/09/13

REPOSITORIES: GEO