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Suppression of endogenous CBS promotes Ferroptosis.

ABSTRACT: To identify the gene profile change caused by cystine depletion, we compared the whole-genome transcriptional profiling of colorectal cancer cells in the full medium (FM) or cystine-restricted medium (CR). We analyzed the early regulatory events in the course of ferroptosis via whole-genome transcriptional analysis of gene expression of cells under FM or CR mediums

ORGANISM(S): Homo sapiens

PROVIDER: GSE213535 | GEO | 2022/11/16

REPOSITORIES: GEO

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Lysosomal cystine governs ferroptosis sensitivity in cancer via nuclear cysteine response

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CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy

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LINC01133 can induce acquired resistance to ferroptosis in pancreatic cancer by enhancing the mRNA stability of FSP1 through forming the LINC01133-FUS-FSP1 complex [circRNA]

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LINC01133 can induce acquired resistance to ferroptosis in pancreatic cancer by enhancing the mRNA stability of FSP1 through forming the LINC01133-FUS-FSP1 complex [miRNA-seq]

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