DYRK2 gene transfer suppresses liver tumorigenesis

ABSTRACT: We generated liver-specific Dyrk2 knockout mice mating Dyrk2 flox mice with Alb-cre mice and co-introduced SB13-transposase-, myrAkt-, Myc- and mutant Hras-expressing plasmids with either HA- or Dyrk2-expressing plasmid into the knockout mice by HTVi. Dyrk2-expressing suppressed tumorigenesis compared with HA-expressing.

ORGANISM(S): Mus musculus

PROVIDER: GSE214053 | GEO | 2022/09/24

REPOSITORIES: GEO