Transcriptional profiling of Cd169-lineage lymph node macrophages

ABSTRACT: Tingible body macrophages (TBMs) exist in lymph node B cell follicles and are responsible for clearing apoptotic B cells. Our data suggests that TBMs are of Cd169-lineage. We isolated cells from Cd169Cre/+.Tdtomatofl/fl reporter mice and transcriptionally profiled them to identify putative TBMs and chacterise their development and function relative to other LN cells of the Cd169 lineage.

ORGANISM(S): Mus musculus

PROVIDER: GSE214060 | GEO | 2023/02/16

REPOSITORIES: GEO